Transposable elements and the evolution of eukaryotic genomes

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Transposable elements and the evolution of eukaryotic genomes.

W hen transposable elements (TEs) were discovered in maize by Barbara McClintock 50 years ago they were regarded as a curiosity; now they are known to be the most abundant component of probably all eukaryotic genomes. They account for almost 50% of the human genome and 70% of the genomes of some grass species, including maize. As such, they make up the vast majority of the output of genome sequ...

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Transposable elements and the evolution of eukaryotic complexity.

Eukaryotic transposable elements are ubiquitous and widespread mobile genetic entities. These elements often make up a substantial fraction of the host genomes in which they reside. For example, approximately 1/2 of the human genome was recently shown to consist of transposable element sequences. There is a growing body of evidence that demonstrates that transposable elements have been major pl...

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Eukaryotic Transposable Elements: Teaching Old Genomes New Tricks

When transposable elements were discovered in maize by Barbara McClintock over 50 years ago they were regarded as a curiosity—now they are known to be to the most abundant component of probably all eukaryotic genomes. As such, they make up the vast majority of the output of genome sequencing projects. The availability of so much new information has fueled a revolution in their analysis and stud...

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Evolution and Diversity of Transposable Elements in Vertebrate Genomes

Transposable elements (TEs) are selfish genetic elements that mobilize in genomes via transposition or retrotransposition and often make up large fractions of vertebrate genomes. Here, we review the current understanding of vertebrate TE diversity and evolution in the context of recent advances in genome sequencing and assembly techniques. TEs make up 4-60% of assembled vertebrate genomes, and ...

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The comparative sequencing of several grass genomes has revealed that transposable elements are largely responsible for extensive variation in both intergenic and local genic content, not only between closely related species but also among individuals within a species. These observations indicate that a single genome sequence might not reflect the entire genomic complement of a species, and pro...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2006

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0607612103